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Sage is an herb. There are lots of types of sage. The two most common prevail sage (salvia officinalis) and spanish sage (salvia lavandulaefolia).

Sage might aid with chemical imbalances in the brain that cause issues with memory and thinking abilities. It may likewise alter how the body uses insulin and sugar.

Individuals frequently use sage for memory and thinking skills, high cholesterol, and signs of menopause. It is likewise used for discomfort after surgical treatment, lung cancer, aching throat, sunburn, and many other conditions, but there is no good scientific proof to support these usages. [2]


Salvia officinalis has been utilized since ancient times for warding off evil, snakebites, increasing females’s fertility, and more. The romans described sage as the “holy herb,” and employed it in their spiritual routines. Theophrastus discussed 2 various sages, a wild undershrub he called sphakos, and a similar cultivated plant he called elelisphakos. Pliny the senior stated the latter plant was called salvia by the romans, and used as a diuretic, a local anesthetic for the skin, a styptic, and for other uses. Charlemagne advised the plant for cultivation in the early midlifes, and during the carolingian empire, it was cultivated in abbey gardens. Walafrid strabo explained it in his poem hortulus as having a sweet scent and being useful for many human ailments– he went back to the greek root for the name and called it lelifagus.

The plant had a high credibility throughout the midlifes, with lots of expressions referring to its recovery residential or commercial properties and worth. It was sometimes called s. Salvatrix (sage the hero). Dioscorides, pliny, and galen all advised sage as a diuretic, hemostatic, emmenagogue, and tonic. Le menagier de paris, in addition to advising cold sage soup and sage sauce for poultry, advises infusion of sage for cleaning hands at table. John gerard’s herball (1597) specifies that sage “is singularly good for the head and brain, it quickeneth the senses and memory, strengtheneth the sinews, restoreth health to those that have the palsy, and taketh away shakey shivering of the members.” gervase markham’s the english huswife (1615) provides a dish for a tooth-powder of sage and salt. It appears in recipes for 4 burglars vinegar, a blend of herbs which was supposed to fend off the plague. In previous centuries, it was also used for hair care, insect bites and wasp stings, nervous conditions, psychological conditions, oral preparations for swelling of the mouth, tongue and throat, and also to reduce fevers. [3]


Sage (salvia officinalis) is belonging to the mediterranean and naturalized throughout europe and north america. Referred to as garden sage, meadow sage, and true sage, this pungent herb belongs to the lamiaceae, or mint, household. The genus name is drawn from the latin salvare significance “to save.” the specific name officinalis indicates that sage was consisted of on official lists of medicinal herbs. There are numerous species of sage, consisting of clary sage (s. Sclarea) named because of its standard usage as an eyewash. Native americans used the roots and leaves of lyre-leafed sage (s. Lyrata l.), also known as cancerweed, as a salve for sores and in a tea to deal with colds and coughs. Another types, known as divine sage (s. Divinorum), a local of oaxaca, mexico, has actually been used for centuries by regional shamans to accomplish modified states of consciousness in recovery routines. There are many more garden varieties, including red or purple sage (s. Officinalis purpurascens), which is valued particularly for its medical purposes.

Sage prospers in full sun and well-drained soils, growing wild in some areas. It is a durable evergreen shrub with a deep taproot and an erect root stalk that produces woody, square, a little downy, branching stems that may reach a height of 4 feet (1.2 m). This familiar garden seasonal has long, light-green leaf stalks that bear easy opposite lance- or oval-shaped leaves. The strong and flexible leaves are veined, with a velvet-like rather crinkled texture and may grow to 2 in (5.1 cm) long in some varieties. Leaf margins resemble a fine embroidery finish with rounded minutely toothed edges. They are a gray-green on the top and lighter on the underside. The whole plant is highly fragrant, with a familiar pungency. Fresh leaves are bitter to the taste. Sage blossoms in the middle of summer season with little white, blue, or purple flowers. [4]


Basic requirements sage is a grows finest in a well draining pipes, rich, clay loams with a ph between 6.5 and 7.0. It must be planted in full sun, although some afternoon shade is tolerated. Sage plants require warm temperatures and adequate sunshine in order to produce a high important oil material in the leaves. Propagation sage is normally propagated from seed, although both cuttings, divisions and air layering is also successfully practiced. The planting website should be warm, dry and safeguarded from wind. Seeds ought to be sown after all risk of frost has actually passed leaving 23 cm (9 in) between seeds. Fertilizer may be contributed to the soil prior to planting to help advancement. Plants should be thinned to a final spacing of 45 cm (18 in). General care and maintenance sage plants should be pruned in early spring to promote brand-new development, or after blooming in the summer. In addition to an application at planting, sage will gain from a side dressing of fertilizer 6 to 8 weeks after planting. Sage will end up being very woody within 3-4 years of planting and must be changed with new plants. Collecting sage is best gathered right before flowering when the important oil material of the leaves is highest. Sage should be harvested by cutting the top 20 cm (8 in) of tender development with a sharp knife. Business fields may be gathered by trimming however the highest quality item is attained by gathering just the leaves. [5]

Culinary sage types

The two main types of sage that are grown for their cooking usages include ‘berggarten ‘, or standard german sage, and the ever-popular ‘broadleaf ‘. While lots of people prefer to grow garden sage for cooking and its rich taste, broadleaf sage has a milder flavor, making it preferable for pickling or contributing to meals and even cheese.

Garden sage is a sturdy seasonal if you reside in strength zones 5-8 in the united states. It’s likewise resistant to insects and illness, so while you will require to remove little bugs from the plant, it will not need much work from you to keep it healthy.

Typical sage

Likewise called: culinary sage, garden sage.

Scientific name: salvia officinalis.

Common sage leaves

Common sage is a popular herb that is grown for both medicinal and culinary uses. It’s an easy-to-grow perennial plant that can handle most of the harsher climates in the northern united states, as well as in colder areas.

It grows best in raised beds with clayey soils completely sun to partial shade. Make sure it has complete drainage. You must likewise try to find great air flow around this plant to help avoid bugs such as spider termites from damaging it or infecting it with illness.

Broadleaf sage

Also known as: cooking sage.

Broadleaf sage

Scientific name: salvia nemorosa ‘hot globe’ a terrific plant to add to your vegetable garden if you like matching fresh herbs with meals. The leaves can be used in both mouthwatering meals or desserts. This range of sage is also a great choice if there are kids (or animals) in your house due to the fact that it has a milder taste than other kinds of sage. It also works well for pickling and seasoning oils, vinegars, butters and cheeses.

Golden sage

Taxonomic name: salvia officinalis ‘aurea’ and salvia officinialis ‘icterina’.

Golden sage

Golden sage has a less pungent flavor than typical garden sage, and frequently has a minor citrus taste.

Golden sage doesn’t fare very well in colder environments and tends to be more sensitive to modifications in light or temperature than other types of sage. These garden varieties tend to be more sensitive to other pests and diseases as well. But it is durable to about 20 degrees fahrenheit but can grow back from the roots if exposed to cooler temperatures.

Russian sage

Taxonomic name: perovskia atriplicifolia.

Russian sage

Russian sage is a stunning and aromatic blooming plant, however it can also be grown for cooking functions. Native to russia, central asia and turkey, this perennial herb is hardy in usda zones 4 through 9 with a preference for zones 5 through 8. It has long flowering periods that face fall or winter season and frequently reseeds itself the following spring.

The colors of russian sage flowers and leaves are mainly shades of purple. As a seasonal, they can mature to 2 feet high with 2-inch long leaves growing in opposite pairs on the stem. The blooms are typically violet to pinkish or purple but may also be white.

Herbalists consider this plant mildly astringent and frequently utilize it as a hair wash for dry or breakable hair. It is also effective in alleviating swelling of your mucous membranes, such as those discovered in the throat or mouth and nasal passages.

An infusion of russian sage has been used to treat colds, aching throats and coughs when added to beverages such as tea.

Italian sage

Likewise called: italian aromatic sage.

Scientific name: salvia officinalis ‘italian’.

Italian sage

Italian sage has big violet flowers with grey leaves. This range of culinary sage isn’t frequently utilized for medical purposes, and it is a good choice if you wish to grow it for decorative factors. It grows up to 2 feet high with opposite, ovate leaves that have to do with 1 inch in length.

Greek sage

Also called: salvia cypria.

Scientific names: salvia fruticosa.

Greek sage

Typical uses: this type of sage is belonging to the mediterranean area and is used mainly for ornamental factors. It matures to 3 feet high with slim stems and dark green leaves. Its blue-purple flowers are typically used in arrangements and dried flower plans.

Greek sage is durable in usda zones 5 through 9 and chooses to grow in full sun. It belongs to the mint family, so it can self-sow if offered sufficient water.

Greek sage represent 50-95% ( of the dried sage offered in north america, so to say it’s popular is an understatement.

Scarlet sage

Also known as: scarlet salvia.

Taxonomic name: salvia splendens.

Scarlet sage

A special range of sage with dynamic red or purple flowers, this plant has an extremely fragrant aroma that can be utilized to make a variety of organic products. The growing ideas are the most powerful part of the plant, but you can also harvest them for usage in sachets or other aromatic products. You can even dry and squash the leaves to produce your own potpourri.

Plants will reach around 2 feet high and expanded into a dense bush with their timeless oval green leaves. Like numerous perennials, you should cut back on water during the winter season when temperatures drop below freezing.

Pineapple sage

Likewise called: sweet sage.

Taxonomic name: salvia elegans.

Pineapple sage

This range gets its name from the sweet odor it has when it blooms. Pineapple sage likewise grows well as a decorative herb with small purple flowers and green leaves. You can utilize this range to make both a tea and tincture or harvest the leaves for later use.

Typical usages for this plant include helping indigestion, minimizing pain related to menstrual cramps, soothing symptoms of anxiety and assisting you get a relaxing night’s sleep.

Pineapple sage is sturdy in usda zones 5 through 9 with a preference for zones 7 through 8. It is a yearly blooming plant that can grow up to 4 feet tall and 2 feet large. It has soft green leaves that are somewhat serrated, giving it a special look when compared to other plants in the salvia genus.

Pineapple sage is popular for its fragrant purple flowers with yellow centers however also makes an appealing decorative plant due to its dark green foliage and low-growing stature. The flowers will appear from late summer season into fall or early winter on this hardy yearly. They have a pineapple aroma that attracts bees and butterflies while including color to your garden beds during those months when many other blooming herbs stop working to do so.

The little flowers are densely compacted with their purplish-red petals radiating from a yellow center. The plant itself will mature to 4 feet high, however it can also expand into a wider bush with some pruning and correct care.

White sage

Scientific name: salvia apiana.

White sage

White sage has silvery gray leaves and is typically utilized as the normal “sage burning” sage. Native to the southwestern regions of the united states and mexico. It is typically dried for ritualistic usage, burning as a smudge stick. White sage has a strong, pine-like fragrance with a smokey finish. It is extremely valued for ritualistic use by numerous native individuals.

Many varieties of white sage are not recommended for culinary use because they tend to have more of a scorched flavor than other ranges. White sage is also extremely sturdy, and can be grown in zones 5 to nine.

Mealycup sage

Scientific name: salvia farinacea.

Mealycup sage

Mealycup sage is belonging to texas and the desert locations of brand-new mexico. The leaves are blue-green or grey, with downy hairs beneath, and grow close together along the stems that can grow between 12 and 24 inches tall. Mealycup sage is also called texas tarragon because it tastes like its french cousin when utilized in cooking. Herbalists utilize this plant to assist soothe indigestions, decrease tension and deal with diarrhea.

The flowers on the mealycup sage are lilac-blue, white or pink relying on the range you pick. This sturdy perennial grows best in usda zones 8 through 11 however will grow in zone 6 if offered the right amount of water. You can cut back on the quantity you provide it during the winter months when temperatures drop below freezing. Just don’t allow the plant to wilt entirely.

Mealycup sage must be planted in a sunny spot in either full or partial sun and watered regularly. Nevertheless, this particular variety doesn’t succeed with overwatering– keep the soil a little dry in between watering sessions. This is specifically true if utilizing a drip watering system– excessive water will eliminate your plant off rather rapidly. If you use sprinklers, wait until after sundown so the leaves have time to fully dry before early morning dew appears.

The seeds for mealycup sage are white and grow within pods that are generally around 1 inch.

Mexican bush sage

Taxonomic name: salvia leucantha.

Mexican bush sage

This variety of sage is native to mexico and main america. It grows between 2 and 3 feet tall and has actually deeply colored, dark green foliage. Mexican bush sage is frequently used as a border plant in the landscape due to its capability to grow on high slopes and endure hot weather conditions with routine watering.

The small purple flowers flower from july through september on this hardy perennial plant however you can likewise harvest leaves for tea or drying when it flowers so the plant stays healthy.

You might discover that pinch back your mexican bush sage every few years throughout early spring at around 10 inches high if you prefer it as simply an ornamental flower since they are extremely large bushes once they get to a specific size.

Berggarten sage

Scientific name: artemisia berggardiana.

Berggarten sage

This variety of sage is frequently used for decorative purposes because of its appealing gray-green leaves. It grows between 1 and 2 ′ high with a spread of as much as 3 ′. As the name suggests, berggarten sage grows finest in an environment zone 7 or greater but will do alright in zones 5 through 9 if given the correct amount of water– it doesn’t like to dry totally!

The flowers flower blue from mid-july into august on this durable seasonal plant, however you can likewise harvest fresh leaves throughout summer season for usage in your cooking productions so the plant remains healthy. If you pinch the tips off of your berggarten sage every couple of years in early spring at about 8 inches tall, you can motivate it to grow bushier and thicker.

Woodland sage

Likewise referred to as: wood sage.

Scientific name: salvia nemorosa.

Forest sage

Woodland sage is a perennial plant that grows to about 3 feet in height and has green leaves with purple markings. The plant can be used as a border for open woods or planted near taller plants. The fragrance of the blooms is stated to bring in bees, butterflies, and birds.

Woodland sage spreads by rhizomes, and while they don’t trigger any damage, they do grow on top of the ground. For this reason, forests sage is often grown in containers or raised beds. These plants can be grown in usda zones 4 through 8 and are relatively dry spell tolerant throughout the summertime.

Woodland sage is typically utilized for medicinal purposes. It has actually been understood to treat nervousness, vomiting, and diarrhea. The leaves are also utilized for teas in some cultures as a treatment for colds, coughs, and fevers.

It can be grown outdoors or as part of an indoor garden however is regularly discovered growing outside near the woods or other gardens where it tends to prosper finest. This plant is best grown from seed and it is necessary not to overwater or fertilize forest sage plants. [6]

Advantages of sage

Sage is a staple herb in various foods around the globe.

Its other names consist of common sage, garden sage and salvia officinalis. It belongs to the mint household, alongside other herbs like oregano, rosemary, basil and thyme.

Sage has a strong aroma and earthy taste, which is why it’s usually utilized in small amounts. However, it’s loaded with a range of essential nutrients and substances.

Sage is likewise used as a natural cleaner, pesticide and routine things in spiritual sage burning or smudging.

This green herb is offered fresh, dried or in oil kind– and has numerous health advantages.

Here are 12 unexpected health benefits of sage.

High in a number of nutrients

Sage packs a healthy dosage of vitamins and minerals.

One teaspoon (0.7 grams) of ground sage consists of:.

  • Calories: 2
  • Protein: 0.1 grams
  • Carbs: 0.4 grams
  • Fat: 0.1 grams
  • Vitamin k: 10% of the
  • Reference daily intake (rdi)
  • Iron: 1.1% of the rdi
  • Vitamin b6: 1.1% of the rdi
  • Calcium: 1% of the rdi
  • Manganese: 1% of the rdi

As you can see, a small amount of sage loads 10% of your everyday vitamin k needs (2trusted source).

Sage also contains small amounts of magnesium, zinc, copper and vitamins a, c and e.

What’s more, this aromatic spice homes caffeic acid, chlorogenic acid, rosmarinic acid, ellagic acid and rutin– all of which contribute in its advantageous health impacts.

Because it’s consumed in tiny quantities, sage supplies only tiny quantities of carbohydrates, calories, protein and fiber.

Summary sage is

Rich in nutrients– especially vitamin k– despite being low in calories. One.

Teaspoon (0.7 grams) boasts 10% of your daily vitamin k requirements.

Loaded with anti-oxidants

Anti-oxidants are particles that help strengthen your body’s defenses, neutralizing potentially harmful free radicals that are linked to chronic diseases.

Sage consists of over 160 unique polyphenols, which are plant-based chemical substances that function as anti-oxidants in your body.

Chlorogenic acid, caffeic acid, rosmarinic acid, ellagic acid and rutin– all found in sage– are linked to excellent health benefits, such as a lower threat of cancer and improved brain function and memory.

One study found that drinking 1 cup (240 ml) of sage tea twice everyday considerably increased antioxidant defenses. It also decreased both overall cholesterol and “bad” ldl cholesterol, in addition to raised “good” hdl cholesterol.

Summary sage is

Packed with antioxidants that are connected to several health benefits, consisting of.

Improved brain function and lower cancer threat.

May support oral health

Sage has antimicrobial results, which can reduce the effects of microorganisms that promote oral plaque.

In one research study, a sage-based mouthwash was revealed to efficiently eliminate the streptococcus mutans bacteria, which is infamous for triggering dental cavities.

In a test-tube research study, a sage-based vital oil was revealed to eliminate and stop the spread of yeast albicans, a fungi that might likewise cause cavities.

One evaluation kept in mind that sage may deal with throat infections, oral abscesses, contaminated gums and mouth ulcers. However, more human research study is needed to make detailed recommendations.

Summary sage

Has antimicrobial homes that might kill microbes that encourage the development.

Of oral plaque.

May ease menopause symptoms

During menopause, your body experiences a natural decrease in the hormone estrogen. This can cause a large range of undesirable signs.

Signs consist of hot flashes, extreme sweating, vaginal dryness and irritability.

Common sage was traditionally utilized to decrease menopause symptoms.

It’s thought that compounds in sage have estrogen-like residential or commercial properties, allowing them to bind to certain receptors in your brain to assist improve memory and deal with hot flashes and extreme sweating.

In one research study, day-to-day use of a sage supplement considerably reduced the number and strength of hot flashes over eight weeks.

Summary sage

May help reduce the strength and frequency of menopause signs, such as hot

Flashes and irritability.

May decrease blood glucose levels

The leaves of typical sage have been used generally as a treatment versus diabetes.

Human and animal research study indicates that it may help lower blood sugar levels.

In one research study, sage extract decreased blood glucose levels in rats with type 1 diabetes by activating a particular receptor. When this receptor is activated, it can help clear excess totally free fatty acids in the blood, which in turn improves insulin level of sensitivity.

Another study in mice with type 2 diabetes found that sage tea imitates metformin– a drug recommended to manage blood sugar level in individuals with the very same disease.

In people, sage leaf extract has actually been shown to lower blood sugar level and improve insulin level of sensitivity with a comparable result as rosiglitazone, another anti-diabetes drugs.

However, there is still insufficient proof to suggest sage as a diabetes treatment. More human research study is needed.

Summary while

Sage might reduce blood glucose levels by increasing insulin sensitivity, more human research study is needed.

May support memory and brain health

Sage can assist support your brain and memory in a number of methods

For one, it’s packed with compounds that can act as antioxidants, which have actually been revealed to buffer your brain’s defense system.

It also appears to halt the breakdown of the chemical messenger acetylcholine (ach), which has a role in memory. Ach levels appear to fall in alzheimer’s illness.

In one study, 39 individuals with moderate to moderate alzheimer’s illness consumed either 60 drops (2 ml) of a sage extract supplement or a placebo daily for four months.

Those taking the sage extract performed much better on tests that determined memory, problem-solving, thinking and other cognitive abilities.

In healthy grownups, sage was shown to improve memory in low dosages. Higher dosages likewise raised mood and increased awareness, calmness and contentedness.

In both more youthful and older grownups, sage appears to enhance memory and brain function.

Summary studies

Show that sage may improve memory, brain function and signs of alzheimer’s.


May lower ‘bad’ ldl cholesterol

Every minute, more than one person in the us dies from cardiovascular disease.

High “bad” ldl cholesterol is a crucial cardiovascular disease threat factor, impacting one in three americans.

Sage might help lower “bad” ldl cholesterol, which can develop in your arteries and possibly trigger damage.

In one study, consuming sage tea twice everyday decreased “bad” ldl cholesterol and overall blood cholesterol while raising “excellent” hdl cholesterol after simply two weeks.

Numerous other human research studies highlight a similar result with sage extract.

Summary consumption

Of sage and sage items have actually been shown to lower “bad” ldl cholesterol levels.

And raise “excellent” hdl cholesterol levels.

May protect against certain cancers

Cancer is a leading cause of death in which cells grow abnormally.

Surprisingly, animal and test-tube studies demonstrate that sage might battle certain types of cancer, consisting of those of the mouth, colon, liver, cervix, breast, skin and kidney.

In these studies, sage extracts not just suppress the growth of cancer cells however likewise promote cell death.

While this research study is motivating, human studies are required to determine whether sage works at combating cancer in people.

Summary test-tube

And animal research recommend that sage might combat certain cancer cells, however.

Human research study is required.

Other possible health advantages

Sage and its substances are linked to several other health advantages.

However, these benefits have not been extensively investigated.

Might reduce diarrhea: fresh sage is a.

Standard treatment for diarrhea. Test-tube and animal research studies discovered that.

It includes substances that may minimize diarrhea by unwinding your diet plan.

May assistance bone health: vitamin k,

Which sage uses in large quantities, plays a role in bone health. A shortage in this vitamin.

Is linked to bone thinning and fractures.

May fight skin aging: numerous test-tube

Research studies recommend that sage substances might help battle indications of aging, such as wrinkles.

Summary sage

Has actually been linked to other potential health benefits, such as eliminating diarrhea,.

Supporting bone health and fighting skin aging.

Easy to contribute to your diet plan

Sage is available in numerous kinds and can be utilized in a range of methods.

Fresh sage leaves have a strong fragrant flavor and are best used sparingly in dishes.

Here are some ways you can add fresh sage to your diet:.

  • Sprinkle as a garnish on soups.
  • Mix into a stuffing in roast dishes.
  • Integrate chopped entrusts butter to make sage butter.
  • Add sliced delegates tomato sauce.
  • Serve it with eggs in an omelet.

Dried sage is often preferred by cooks and comes ground, rubbed or in whole leaves.

Here are some methods you can utilize dried sage:.

  • As a rub for meats.
  • As a seasoning for roasted veggies.
  • Combined with mashed potatoes or squash for earthy taste.

You can also buy sage items, such as sage tea and sage extract supplements.

Summary sage is

Exceptionally flexible and simple to add to soups, stews and baked dishes. It’s.

Offered fresh, dried or ground. [7]

Possible negative effects

When consumed as a spice in food, sage is thought about safe for grownups and children.

Health care experts typically agree that:.

Sage needs to be safe when taken in medical amounts for no more than two months.

Sage may be unsafe when it’s taken in high dosages or for a long period of time. Some types of sage, including typical sage (salvia officinalis), contain a chemical called thujone. Too much thujone can trigger seizures and damage the liver and nervous system.

Sage applied to the skin is potentially safe when utilized for up to one week.

Sage important oil, inhaled as aromatherapy, ought to be safe. Like some other necessary oils, sage oil can be harmful and need to never be taken orally. Even when applied topically, the oil must be diluted or it might cause rash or inflammation.

Sage can also make anticonvulsant drugs less efficient if used in excess, consisting of phenobarbital, mysoline (primidone), depakote (valproic acid), neurontin (gabapentin), tegretol (carbamazepine), and dilantin (phenytoin).

The extreme use of sage if you’re taking diabetes medications can trigger a potentially severe drop in blood sugar level, leading to hypoglycemia. If you utilize sage pills or extracts, never ever consume more than the advised dosage on the item label. Sage medications must be used with care in people with impaired kidney function.

Tell your healthcare provider about any medications you’re taking, consisting of organic remedies like sage, so that you’re completely aware of the potential interactions and dangers. [8]


Dosages of 300 and 600 mg of dried sage leaf have been investigated in mood and cognitive efficiency research studies. A standardized s. Officinalis ethanolic extract at a dose of 333 mg was used in a research study assessing its results on memory and attention in healthy older volunteers. A normal dosage has been referred to as 4 to 6 g/day of the sage leaf. [9]


Drying medications (anticholinergic drugs) interaction ranking: moderate beware with this combination. Talk with your health supplier.

Common sage (salvia officinalis) and spanish sage (salvia lavandulaefolia) may increase levels of certain chemicals in the body that work in the brain, heart, and somewhere else. Some drying medications called “anticholinergic drugs” can likewise these same chemicals, however in a different way. These drying medications may decrease the effects of these sage types, and these sage types may reduce the impacts of drying medications.

Some of these drying medications include atropine, scopolamine, some medications used for allergic reactions (antihistamines), and some medications utilized for depression (antidepressants).

Estrogens interaction score: moderate beware with this mix. Talk with your health supplier.

Geraniol, a chemical in spanish sage (salvia lavandulaefolia), may have some of the very same results as estrogen. However, geraniol found in spanish sage isn’t as strong as estrogen pills. Taking spanish sage along with estrogen tablets might reduce the effects of estrogen pills.

Some estrogen tablets consist of conjugated equine estrogens (premarin), ethinyl estradiol, estradiol, and others.

Medications altered by the liver (cytochrome p450 2c19 (cyp2c19) substrates) interaction rating: moderate beware with this mix. Talk with your health provider.

Some medications are changed and broken down by the liver. Sage may decrease how rapidly the liver breaks down some medications. Taking sage along with some medications that are broken down by the liver might increase the impacts and side effects of some medications. Prior to taking sage as a medication, talk with your healthcare provider if you take any medications that are changed by the liver.

Some medications that are altered by the liver consist of omeprazole (prilosec), lansoprazole (prevacid), and pantoprazole (protonix); diazepam (valium); carisoprodol (soma); nelfinavir (viracept); and others.

Medications changed by the liver (cytochrome p450 2c9 (cyp2c9) substrates) interaction score: moderate beware with this mix. Talk with your health company.

Some medications are altered and broken down by the liver. Sage may decrease how quickly the liver breaks down some medications. Taking sage in addition to some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking sage as a medicine, speak with your doctor if you take any medications that are altered by the liver.

Some medications that are altered by the liver consist of diclofenac (cataflam, voltaren), ibuprofen (motrin), meloxicam (mobic), and piroxicam (feldene); celecoxib (celebrex); amitriptyline (elavil); warfarin (coumadin); glipizide (glucotrol); losartan (cozaar); and others.

Medications altered by the liver (cytochrome p450 2d6 (cyp2d6) substrates) interaction rating: moderate be cautious with this mix. Talk with your health supplier.

Some medications are changed and broken down by the liver. Sage might decrease how rapidly the body breaks down some medications. Taking sage in addition to some medications that are altered by the liver can increase the impacts and negative effects of your medication. Before taking sage as a medicine, speak with your doctor if you take any medications that are altered by the liver.

Some medications that are changed by the body include amitriptyline (elavil), codeine, desipramine (norpramin), flecainide (tambocor), fluoxetine (prozac), ondansetron (zofran), tramadol (ultram), and others.

Medications changed by the liver (cytochrome p450 2e1 (cyp2e1) substrates) interaction rating: moderate be cautious with this combination. Talk with your health supplier.

Some medications are changed and broken down by the liver. Common sage might increase how rapidly the liver breaks down some medications. Taking typical sage in addition to some medications that are changed by the liver may reduce the impacts and adverse effects of your medication. Prior to taking common sage as a medicine, talk with your healthcare provider if you take any medications that are changed by the liver.

Some medications that are changed by the liver consist of acetaminophen, chlorzoxazone (parafon strength), ethanol, theophylline, and substance abuse for anesthesia during surgical treatment such as enflurane (ethrane), halothane (fluothane), isoflurane (forane), and methoxyflurane (penthrane).

Medications changed by the liver (cytochrome p450 3a4 (cyp3a4) substrates) interaction rating: moderate beware with this combination. Talk with your health service provider.

Some medications are changed and broken down by the liver. Sage might decrease how quickly the liver breaks down some medications. Taking sage along with some medications that are broken down by the liver may increase the results and adverse effects of these medications. Before taking sage as a medicine, talk with your doctor if you are taking any medications that are changed by the liver.

Medications that might be impacted include certain heart medications called calcium channel blockers (diltiazem, nicardipine, verapamil), cancer drugs (etoposide, paclitaxel, vinblastine, vincristine, vindesine), fungus-fighting drugs (ketoconazole, itraconazole), glucocorticoids, alfentanil (alfenta), cisapride (propulsid), fentanyl (sublimaze), lidocaine (xylocaine), losartan (cozaar), midazolam (versed), and others.

Medications for alzheimer’s illness (acetylcholinesterase (pains) inhibitors) interaction rating: moderate beware with this mix. Talk with your health provider.

Typical sage (salvia officinalis) and spanish sage (salvia lavandulaefolia) may increase particular chemicals in the brain, heart, and somewhere else in the body. Some medications utilized for alzheimer’s disease also affect these chemicals. Taking these species of sage along with medications for alzheimer’s illness may increase impacts and negative effects of medications utilized for alzheimer’s disease.

Medications for diabetes (antidiabetes drugs) interaction rating: moderate be cautious with this combination. Talk with your health provider.

Sage may decrease blood glucose. Diabetes medications are likewise utilized to lower blood sugar. Taking sage along with diabetes medications might trigger your blood glucose to go too low. Monitor your blood sugar level carefully. The dosage of your diabetes medication may require to be altered.

Some medications used for diabetes include glimepiride (amaryl), glyburide (diabeta, glynase prestab, micronase), insulin, pioglitazone (actos), rosiglitazone (avandia), chlorpropamide (diabinese), glipizide (glucotrol), tolbutamide (orinase), and others.

Medications for high blood pressure (antihypertensive drugs) interaction rating: moderate beware with this mix. Talk with your health supplier.

Common sage (salvia officinalis) appears to lower blood pressure. Taking typical sage along with medications for hypertension may cause your blood pressure to go too low. On the other hand, spanish sage (salvia lavandulaefolia) might increase high blood pressure. Taking spanish sage in addition to medications for hypertension might decrease the effects of these medications.

Some medications for high blood pressure include captopril (capoten), enalapril (vasotec), losartan (cozaar), valsartan (diovan), diltiazem (cardizem), amlodipine (norvasc), hydrochlorothiazide (hydrodiuril), furosemide (lasix), and many others.

Medications moved by pumps in cells (p-glycoprotein substrates) interaction score: moderate be cautious with this combination. Talk with your health supplier.

Some medications are moved by pumps into cells. Common sage (salvia officinalis) might make these pumps less active and increase just how much of some medications get soaked up by the body. This may increase the adverse effects of some medications.

Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, corticosteroids, erythromycin, cisapride (propulsid), fexofenadine (allegra), cyclosporine, loperamide (imodium), quinidine, and others.

Medications used to prevent seizures (anticonvulsants) interaction score: moderate beware with this mix. Talk with your health company.

Medications utilized to prevent seizures affect chemicals in the brain. Sage might also impact chemicals in the brain. By affecting chemicals in the brain, sage may decrease the efficiency of medications utilized to prevent seizures.

Some medications used to prevent seizures include phenobarbital, primidone (mysoline), valproic acid (depakene), gabapentin (neurontin), carbamazepine (tegretol), phenytoin (dilantin), and others.

Sedative medications (benzodiazepines) interaction rating: moderate beware with this mix. Talk with your health supplier.

Common sage (salvia officinalis) might cause drowsiness and drowsiness. Medications that cause sleepiness and sleepiness are called sedatives. Taking common sage together with sedative medications may trigger too much sleepiness.

Some of these sedative medications consist of clonazepam (klonopin), diazepam (valium), lorazepam (ativan), and others.

Sedative medications (cns depressants) interaction score: moderate beware with this mix. Talk with your health service provider.

Sage may trigger drowsiness and drowsiness. Medications that causes sleepiness are called sedatives. Taking sage along with sedative medications may trigger too much drowsiness.

Some sedative medications include clonazepam (klonopin), lorazepam (ativan), phenobarbital (donnatal), zolpidem (ambien), and others.

Various medications utilized for glaucoma, alzheimer’s illness, and other conditions (cholinergic drugs) interaction score: moderate be cautious with this mix. Talk with your health supplier.

Common sage (salvia officinalis) and spanish sage (salvia lavandulaefolia) may increase particular chemicals in the brain, heart, and somewhere else in the body. Some medications utilized for glaucoma, alzheimer’s illness, and other conditions also affect these chemicals. Taking these types of sage with these medications might increase the possibility of negative effects.

A few of these medications utilized for glaucoma, alzheimer’s illness, and other conditions consist of pilocarpine (pilocar and others), donepezil (aricept), tacrine (cognex), and others. [10]


Contraindicated in:.

  • Hypersensitivity;
  • Pregnancy and lactation.

Use carefully in:.

  • Seizure disorders;
  • High blood pressure;
  • Diabetes [11]


The goal of this paper is to review the current improvements in the expedition of sage (salvia types) as phytotherapy and to show its potential as a restorative agent. Salvia types might represent a natural, safe, and efficient treatment for lots of illness and their signs. In recent years, with the boost in medicinal knowledge about the beneficial impacts of sage, particularly s. Officinalis, these natural medications with antibacterial, antioxidant, anti-inflammatory, complimentary extreme scavenging, and antitumor activities have been found to be extremely efficient in the advancement of novel natural drugs to prevent, control, and deal with lots of small illness along with more serious and complicated diseases such as diabetes, alzheimer’s, and cancer. It should be born in mind that clinicians need to remain mindful till more definite studies show the security, quality, and efficacy of s. Officinalis. For these reasons, extensive pharmacological and chemical experiments, together with human metabolic research studies must be the focus of our future studies, and further capacity of s. Officinalis needs to be employed in brand-new restorative drugs and offer a basis for future research on the application of medical plants. [12]


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