Table of Contents
Blushwood Berry or Fontainea picrosperma, frequently referred to as the blushwood tree, is a jungle tree in the family Euphorbiaceae endemic to Queensland in Australia, where it grows on the Atherton Tablelands. [1]
Introduction
An anti-cancer drug called EBC-46 has actually been developed from an extract of the fruits of Fontainea picrosperma. Trials have shown that it has activity versus four different kinds of tumours, consisting of basal-cell cancer, cancer malignancy, squamous cell cancer and breast adenocarcinoma. The fruits are poisonous to humans if eaten. [3]
Stem
Massive watery red exudate appearing quickly in the blaze.
Leaves
Oil dots visible with a lens, almost noticeable to the naked eye. Leaf blades about 7-15 x 2-5 cm. Petioles shallowly directed or flattened on the upper surface area, the margins angular or a little winged. Young shoots outfitted in pale yellow-colored hairs. Branch exudate like that in the blaze.
Flowers
Petals in male flowers about 5-6 mm long and about 7-8 mm long in female flowers. Petals densely white, tomentose. Disk orange. Preconceptions ten, radiating like octopus arms.
Fruit
Fruit about 25 mm long and about 20 mm diam. Endocarp rather thick, stellate in transverse section, frequently 5-pointed in transverse section.
Seedlings
Cotyledons broadly ovate, about 45-55 x 30-40 mm, 3-veined at the base. At the tenth leaf stage: leaves lanceolate to ovate, peak acuminate, base obtuse, upper surface of leaf blade glabrous; oil dots little, indistinct, noticeable only with a lens. Seed germination time 26 to 58 days.
Distribution and Ecology
Endemic to NEQ, restricted to the Atherton Tableland. Altitudinal variety from 700-1100 m. Grows as an understory tree in well industrialized rain forest.
Natural History and Notes
Fallen fruit eaten by Cassowaries and Musky Rat-kangaroos. [4]
This trees grow only and specifically In the far north-eastern part of Queensland Australia, in the rain forests grows the Blushwood Berry tree called Hylandia Dockrillii.
It prospers at high elevations of 400 to 1100 meters in the strong rain forest at various places and reaches heights of as much as 25 meters. Blushwood berries are the fruit of the Blushwood tree. The tree’s berries have has exceptional medicinal residential or commercial properties and its main element EBC-46 may take concern in repairing the body immune system and DNA damaged cells in the future of holistic treatments.
Blushwood Berry
Chemical extracts from the berries of Australian blushwood tree (Hylandia dockrillii) have actually shown to be reliable in treating cancers such as melanoma and breast cancer. Blushwood berry trees are said to be specifically seen in the rainforests of Far North Queensland, Australia. However, attempts to grow them in a greenhouse environment are being done.
EBC-46 Extract
Researchers have established a drug called EBC-46 from the compound extracts of blushwood berries which are said to have anticancer residential or commercial properties. Researchers say that the preparation of the drug is a complex strategy and human trials are presently being carried out. The anticancer impacts of this berry were first reported in 2004.
What does it do?
It is thought that the drug acts straight, deprives the cancer cells off their oxygen supply, and also activates the host immune reaction. Cancer cells revealed shriveling, shrinking, and cell death microscopically quickly after direct exposure to the drug.
EBC-46 activates an enzyme called protein kinase C; however, system included is still unsure. Almost 75% of preclinical trials revealed promising outcomes with extremely little relapse in 1-year follow-up duration and no negative effects. The drug was evaluated in easily available growths; however, its role in metastatic growths is yet to be established. Phase 1 clinical human trials in cutaneous strong tumors such as melanoma squamous cell cancer (SCC), head and neck SCC, basal cell carcinoma, and Merkel cell cancer are underway. EBC-46 is a trademarked chemotherapeutic drug.
The seeds then goes through an extracting process, The EBC-46 element is extracted from seeds compounds, made into liquid, strong pills or powder. Finally it gets packaged in the UK’s best business. [5]
How Blushwood Berries Can Damage Cancer Cells Practically Immediately
A study performed at QIMR Berghofer Medical Research Study Institute in Queensland, Australia has recently shed brand-new light on what could become the next big cancer treatment: the blushwood berry (Hylandia dockrillii). This naturally occurring fruit includes substances that began exterminating cancer cells nearly instantly when studied in the laboratory.
Chemotherapy and radiation are poisonous and come with harsh negative effects, frequently making the ill feel much more ill. The current research study on this remarkable berry could imply new, natural treatments for cancer on the horizon.
Blushwood Berries– Where they Originate from
Blushwood berries are the fruit of the blushwood tree, which is known to grow in only one region of the world: the jungles of Far North Queensland, Australia.
These tropical trees are not found anywhere else on the world, however grow in abundance near Australia’s northeastern suggestion.
These specific trees need really specific niche conditions to thrive– conditions which can just be discovered in specific portions of Far North Queensland, Australia.
Considering their effectiveness as proven by the newest cancer research released in PLOS One, some are questioning if they could be grown in a greenhouse environment, so that individuals all over the world could gain from their cancer-killing homes.
Blushwood Berries– What kind of Cancer they Eradicate
The researchers at QIMR Berghofer Medical Research Institute, headed by Dr. Glen Boyle, utilized an experimental drug produced from the seeds of blushwood berries called EBC-46. They utilized this drug to deal with areas of cancer malignancy (the most fatal kind of skin cancer) on canines, felines and horses.
The topics were detected by vets and offered a poor prognosis, many being considered candidates for euthanasia prior to participating in the study.
Amazingly, these animals that had actually been on death’s door prior to the research study had their melanoma tumors vanish after treatment in the laboratory by Dr. Boyle and his team of researchers.
Tumors were Gone within two days
When the EBC-46 was injected into the malignant cells on the topics, the tumors responded by turning a dark color, then falling off.
The derivative from the blushwood berry is thought to cut off oxygen supply to the cancer cells, allowing for the elimination of tumors without the need for surgery, chemotherapy or radiation treatment.
The researchers reported that most of the topics’ growths– formerly considered a lost bring on by vets– were gone within 2 days of being injected with EBC-46.
Under the microscopic lense, the individual cancer cells started shriveling up and dying within simple momentsof entering into contact with the EBC-46.
What the Future of Cancer Treatment Could Be?
The discovery of the efficiency of EBC-46 is interesting news in the world of cancer treatment.
D.r Boyle states the findings of the pre-clinical trials at QIMR Berghofer suggest the drug could be reliable in human clients.
” In many cases the single injection treatment triggered the loss of viability of cancer cells within 4 hours, and ultimately damaged the growths.”.
Dr. Boyle states EBC-46 operate in part by activating a cellular reaction which efficiently cuts off the blood supply to the growth. “In more than 70 per cent of pre-clinical cases, the response and cure was long-lasting and enduring, with really little regression over a period of 12 months.”.
” We must worry at this moment that EBC-46 will only be trialed in the short-term for growths which can be accessed by direct injection or topical application,” Dr Boyle stated.
” There is no proof to suggest EBC-46 would be effective against metastatic cancers.”.
Further studies using human individuals could serve to show the blushwood berry to be nature’s covert cancer remedy. [6]
Human trials for prospective cancer remedy unearthed in Australian jungle underway
Australian researchers are trialling the cancer-fighting homes in fruit from rain forest trees in Far North Queensland.
EBC-46 is a particle found in the berries of the jungle tree blushwood (fontainea picrosperma), which grows on the Atherton Tablelands.
” It’s a little molecule which works with the body to ruin cancer, instead of being a chemo-therapy technique which can act versus the body,” Dr Victoria Gordon, CEO of Q-Biotics, informed TODAY.
She described the ingenious treatment worked by injecting the particle into the tumour website.
” We get full tumour damage in 5 to seven days, excellent healing … and no substantial side effects”.
The results EBC-46 has actually been trialled with animals, including Dr Gordon’s 18-year-old animal dog who had an oral cancer malignancy.
” We injected the drug (EBC-46) and it just appeared to liquefy (the tumour),” she said.
Early stages of human trials are underway, with 14 patients treated up until now.
” We have actually had no significant negative effects and great lead to six tumour types”.
Dr Gordon emphasised there is still a “a long, hard road ahead” prior to a pharmaceutical can be established from the drug. [7]
Appealing ‘cancer-cure’ berries taken off sale for fear of poisonous natural home remedy poisoning
‘ Most of the times the single injection treatment triggered the loss of practicality of cancer cells within four hours, and eventually ruined the tumours,’ lead scientist Dr Glen Boyle informed the ABC.
Sellers of the native tree are scrambling to take the jungle range off sale however, after worries that people could be poisoned attempting to develop homemade cancer treatments.
‘ Our issue was individuals were just going to grow it, get some fruit, crush it up and consume it,’ Roger Smith, manager of Yuruga Native Plant Nursery told the Cairns Post.
Scientist Steven Ogbourne of the University of Sunshine Coast says it’s not that easy, and a complicated procedure is needed to extract the cancer-fighting substance.
Human trials are presently being prepared for the appealing drug. [8]
Conclusion
Fontainea picrosperma (Blushwood) are uncommon small shy spindly dioecious, wet enclosed rainforest understorey trees requiring canopy security. Some Fontaineas species survive in hasher conditions than the Blushwood. F.venosa can grow to 60 feet compared to 15 feet for Blushwood that grows at 2,300 ft to 3,600 ft. Blushwoods hate a cool temperature and require the nutrients, moisture and the protection of a wet rain forest. Alkaloids discovered in all Fontainea sap causes cancerous tumours to ablate, but there are only 200 of these native trees in the world, so you will not legally have the ability to import these plants into the U.S.A. out of Australia. [9]
References
- https://en.wikipedia.org/wiki/Fontainea_picrosperma
- https://apps.des.qld.gov.au/species-search/details/?id=17128
- https://www.herbal-organic.com/en/herb/197290
- https://apps.lucidcentral.org/rainforest/text/entities/fontainea_picrosperma.htm
- https://www.blushwoodforest.co.uk/
- https://www.seychellesweekly.com/2016/February%2015,%202016/beaute-sante1_blushwood_berries.html
- https://www.9news.com.au/health/cancer-fighting-berry-discovered/781a0d81-28f2-4f61-ba56-7895bc3e51ce
- https://www.thatslife.com.au/fears-of-cancer-cure-home-remedy-poisoning
- https://www.daleysfruit.com.au/forum/blushwood2/
